Medical Oncology

  • Bone Marrow Transplant
  • Medical Oncology & Hematology

Zydus Cancer Centre – The Most Comprehensive Set up of Bone Marrow Transplant in Gujarat

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  • The Centre is equipped with ultra-modern infrastructure and internationally trained, widely experienced faculty and BMT unit nursing staff
  • The BMT set up includes 7 rooms, furnished like an ICU, with separate AHU and terminal HEPA filters in each room and the corridor
  • Supported by state-of-the-art laboratory & transfusion services
  • Fully equipped Radiation Oncology unit with facility for total body irradiation
  • Very stringent infection control norms which are critical for BMT patients
  • Amalgamation of Latest technology, Internationally trained experts, state-of-the-art infrastructure & compassionate care
  • Comprehensive team includes:
    • BMT physicians
    • Hemato-oncologist
    • Medical oncologist
    • Radiation oncologist
    • Transfusion medicine expert
    • Hemato-pathologist
    • Trained transplant nurses
    • Infection control specialist
    • Physiotherapist
    • Dietician
    • Counselors
    • BMT coordinator

What is Bone marrow transplant?

Bone Marrow Transplant procedure is performed not only for cancerous conditions like blood cancer, but also for genetic conditions like thalassemia. Here the cancerous or genetically abnormal stem cells are eradicated by chemotherapy and immune suppressive medicines and new functionally normal stem cells are given, which later populate the bone marrow and blood with non-cancerous cells and genetically normal cells.

Types of Bone Marrow Transplant:

  • Autologous Stem cell transplant
    An autologous stem cell transplant, uses healthy blood stem cells from your own body to replace your diseased or damaged bone marrow.
  • Allogeneic stem cell transplant
    Allogeneic stem cell transplant In this procedure a patient receives healthy stem cells (blood-forming cells) to replace their own stem cells that have been destroyed by treatment with radiation or high doses of chemotherapy
  • How Bone Marrow Transplant Works?
    Before stem cell transplant, stem cells are collected from either the bone marrow or the blood. Patient is given high doses of chemotherapy, usually over a few days. Sometimes, radiotherapy is also given to the whole body, known as Total Body Irradiation (TBI). While destroying any remaining cancer cells, the high doses of chemotherapy also destroy the stem cells in the bone marrow. After the chemotherapy, patient is given the stem cells that were collected before the treatment. These stem cells start producing mature blood cells again

Indications

  • Autologous Transplant (Stem Cells collected from one's own body)
    • Hodgkin's & Non Hodgkin's Lymphoma: For relapsed / refractory cases, it is standard therapy and in most such cases, it is the only curative option
    • Myeloma: Although not curative, it is standard treatment as a part of initial therapy, as it prolongs survival substantially
    • Leukemia: Relapsed Acute promyelocytic leukemia
  • Allogenic Transplant (Stem Cells collected from some one else's body)
    • Thalassemia
    • Several other genetic disorders, especially with single gene defects
    • Aplastic Anemia
    • Chronic Myeloid Leukemia
    • High Risk AML & Relapsed AML
    • Relapsed ALL (Acute Lymphocytic Leukemia)
    • As an option in several advanced or refractory haematological malignancies eg. follicular lymphoma, CLL, myeloma etc

What is Medical Oncology?

Medical Oncology is a modality of treatment in cancer care which uses chemotherapy, targeted therapy, hormonal therapy and immunotherapy to treat cancer in an effective manner. Medical Oncology usually works in conjunction with surgical oncology and radiation oncology to give the best clinical outcomes. A medical oncologist is an Expert person who deals in this field.

What is Chemotherapy?

Chemotherapy is a form of drug therapy meant to destroy rapidly growing cancer cells in the body. As cancer cells grows and divide faster than any other cells, Chemotherapy is usually used to. We give Chemotherapy using both conventional and latest protocols that compare with the international standards of care.

Chemotherapy is often used in combination with other therapies, such as surgery, radiation, or hormone therapy. This depends on:

  • The stage and type of cancer you have
  • Your overall health
  • Previous cancer treatments you have undergone
  • The location of the cancer cells
  • Your personal treatment preferences

Also, it is important to note that Chemotherapy is a systemic treatment and works on the entire body.

What is Targeted Therapy?

Targeted Therapy is a cancer treatment that uses drugs, but is different from traditional Chemotherapy. Targeted Therapy works by targeting cancer's specific pathway, proteins, or the tissue environment that contributes to cancer growth and survival. These genes and proteins are found in cancer cells or in cells related to cancer growth, like blood vessel cells. Doctors often use targeted therapy with chemotherapy and other treatments, so as to get maximum results.

What is Immunotherapy?

Immunotherapy, also called biologic therapy, is a type of cancer treatment that boosts the body's natural defense to fight cancer. It uses substances made by the body or in a laboratory to improve or restore immune system function. Immunotherapy works by helping the immune system work better at destroying cancer cells.

Types of Immunotherapy:

  • Cancer vaccines
  • PD-I inhibitors
  • PDL -1 inhibitors
  • CTLA-4 inhibitors

What is Hormone Therapy?

Hormone Therapy is a cancer treatment that slows or stops the growth of cancer that uses hormones to grow. Hormone Therapy is also known as Endocrine Therapy. It is a form of targeted treatment which target specific hormonal pathway

What is Haematology?

Haematology is the science or study of blood, blood forming organs and blood diseases.

Treatment offered in Haematology:

  • Benign haematological problems: anaemia, bleeding disorders, platelet disorders and haemoglobinopathies
  • Haematological malignancies: leukaemia, lymphomas, multiple myeloma, myelo proliferative and lymph proliferative disorders and bone marrow / stem cell transplantation
  • Leukaemia induction / consolidation chemotherapy in adults / paediatrics
  • Out-patient based chemotherapy for myeloma, lymphoma, myelo proliferative, lympho proliferative disorders and some types of leukaemia
  • Offer state-of-the-art bone marrow and stem cell transplantation facilities
  • Autologous and various types of allogeneic stem cell transplantation (syngenic, related, unrelated, cord and haploidentical, to name a few)

Salient Features of Medical Oncology & Haematology:

  • Diagnosis and medical treatment of all type of cancers
  • Chemotherapy and targeted therapy for all types of cancers (day care and indoor facilities)
  • Guidance for screening and prevention of cancer
  • Genetic consultation for hereditary cancer
  • Palliative care and cancer pain management
  • Supportive care for all types of cancers
  • Diagnosis and treatment of blood disorders
  • Blood cancer and other blood disorders
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